Seize Plague Weapons From the Enemy
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Thymesia is sold on an intricate plague weapon system. The publisher describes it plainly: you seize plague weapons from gruesome bosses and formidable enemies, then wield them as deadly weapons of your own.
Find a formidable carrier
The official description does not say plague weapons drop from ordinary street enemies. They come from bosses and formidable opponents, which turns each hard fight into a supply run as much as a wall. If you are short of tools, look at which carrier you have been avoiding rather than which enemy you can farm quickly.
Treat the weapon as borrowed, not banked
The store frames giving enemies a taste of their own medicine as the way to survive the horrors of Hermes, rather than as permanent equipment. That is a hint about how to use them: as a strong answer to a specific problem while you have it, not as a build you can ignore the rest of the fight for.
Keep one answer for the next corridor
Because the Kingdom of Hermes is described as blood-soaked and full of infected monsters, you rarely get a quiet approach to the next fight. Rotate through what the carriers have given you, and keep the strongest tool for the enemy type you find hardest rather than spending it on the first crowd.
Tools only work if you can land them: interrupt with feathers and raven form. Then decide which track to feed first in upgrading movements and weapons together.