Know What Co-op and PvP Add
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Salt and Sacrifice is described as an online co-op successor to Salt and Sanctuary, with full co-op, drop-in quickplay and fast PvP through various factions.
Co-op covers the whole hunt
The description is full online co-op with a fellow Inquisitor, which means a partner can stay for the entire pursuit rather than joining for a boss. For a game built on chasing Mages through a labyrinth, that changes how much of the map you can safely cover.
Quickplay lowers the barrier
Drop-in quickplay is named separately from organising a session, so help does not require planning in advance. That makes the multiplayer a live option during a hunt rather than a separate mode you schedule.
PvP factions are part of the world
Fast and chaotic PvP runs through various factions, which fits a setting where you are a condemned Inquisitor in a divided realm. Treating every encounter as purely PvE is the assumption that PvP exists to break.
Multiplayer is a layer on top of the hunt, covered in hunting the Mages and taking what they leave, with the gear side in runic arts and weapons.