Fallout 4 Wiki
Let S.P.E.C.I.A.L. and perks pick your build, choose between V.A.T.S. and real-time fighting, and treat settlements as infrastructure.
Guides
Starting routes, progression and the decisions that shape a run.
Choose your next guide
Start with the basics, then use the progression and mechanics guides when your next run needs a different approach.
Coverage: PC and console; base game. 3 guides available.
Official Fallout 4 website